Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood

Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood

Severe obesity is a rapidly growing global health threat. Although often attributed to unhealthy lifestyle choices or environmental factors, obesity is known to be heritable and highly polygenic; the majority of inherited susceptibility is related to the cumulative effect of many common DNA variants...

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Main Authors: Khera, Amit V. (Author), Chaffin, Mark (Author), Wade, Kaitlin H. (Author), Zahid, Sohail (Author), Brancale, Joseph (Author), Xia, Rui (Author), Distefano, Marina (Author), Senol-Cosar, Ozlem (Author), Haas, Mary E. (Author), Bick, Alexander (Author), Aragam, Krishna G. (Author), Lander, Eric Steven (Author), Smith, George Davey (Author), Mason-Suares, Heather (Author), Fornage, Myriam (Author), Lebo, Matthew (Author), Timpson, Nicholas J. (Author), Kaplan, Lee M. (Author), Kathiresan, Sekar (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2020-05-13T17:50:30Z.
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