Optogenetic induction of the schizophrenia-related endophenotype of ventral hippocampal hyperactivity causes rodent correlates of positive and cognitive symptoms

Pathological over-activity of the CA1 subfield of the human anterior hippocampus has been identified as a potential predictive marker for transition from a prodromal state to overt schizophrenia. Psychosis, in turn, is associated with elevated activity in the anterior subiculum, the hippocampal outp...

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Main Authors: Wolff, Amy R. (Author), Bygrave, Alexei M. (Author), Sanderson, David J. (Author), Boyden, Edward (Author), Bannerman, David M. (Author), Kullmann, Dimitri M. (Author), Kaetzel, Dennis (Author)
Other Authors: McGovern Institute for Brain Research at MIT (Contributor), Massachusetts Institute of Technology. Media Laboratory (Contributor), Program in Media Arts and Sciences (Massachusetts Institute of Technology) (Contributor)
Format: Article
Language:English
Published: Springer Nature, 2020-05-14T19:00:04Z.
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