Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations
A key public health need is to identify individuals at high risk for a given disease to enable enhanced screening or preventive therapies. Because most common diseases have a genetic component, one important approach is to stratify individuals based on inherited DNA variation 1 . Proposed clinical a...
Main Authors: | , , , , , , , , , , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC,
2020-05-21T19:54:56Z.
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Subjects: | |
Online Access: | Get fulltext |