A Regio- and Enantioselective CuH-Catalyzed Ketone Allylation with Terminal Allenes

We report a method for the highly enantioselective CuH-catalyzed allylation of ketones that employs terminal allenes as allylmetal surrogates. Ketones and allenes bearing diverse and sensitive functional groups are efficiently coupled with high stereoselectivity and exclusive branched regioselectivi...

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Bibliographic Details
Main Authors: Tsai, Erica Y. (Author), Liu, Richard (Author), Yang, Yang (Author), Buchwald, Stephen Leffler (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2020-05-26T18:18:57Z.
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