A Processive Protein Chimera Introduces Mutations across Defined DNA Regions In Vivo

Laboratory time scale evolution in vivo relies on the generation of large, mutationally diverse gene libraries to rapidly explore biomolecule sequence landscapes. Traditional global mutagenesis methods are problematic because they introduce many off-target mutations that are often lethal and can eng...

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Bibliographic Details
Main Authors: Moore, Christopher Lawrence (Author), Papa, Louis John (Author), Shoulders, Matthew D. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2020-05-27T15:13:00Z.
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