Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs
© van de Kooij et al. Human NimA-related kinases (Neks) have multiple mitotic and non-mitotic functions, but few substrates are known. We systematically determined the phosphorylation-site motifs for the entire Nek kinase family, except for Nek11. While all Nek kinases strongly select for hydrophobi...
| Main Authors: | , , , , |
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| Other Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications, Ltd,
2020-05-27T17:03:25Z.
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| Subjects: | |
| Online Access: | Get fulltext |