Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain
Microglia are essential for maintenance of normal brain function, with dysregulation contributing to numerous neurological diseases. Protocols have been developed to derive microglia-like cells from human induced pluripotent stem cells (hiPSCs). However, primary microglia display major differences i...
| Main Authors: | , , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Proceedings of the National Academy of Sciences,
2020-05-27T21:19:35Z.
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| Subjects: | |
| Online Access: | Get fulltext |