XBP1s activation can globally remodel N-glycan structure distribution patterns

XBP1s activation can globally remodel N-glycan structure distribution patterns

Classically, the unfolded protein response (UPR) safeguards secretory pathway proteostasis. The most ancient arm of the UPR, the IRE1-activated spliced X-box binding protein 1 (XBP1s)-mediated response, has roles in secretory pathway maturation beyond resolving proteostatic stress. Understanding the...

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Bibliographic Details
Main Authors: Wong, Madeline Y. (Author), Dewal, Mahender (Author), Taylor, Rebecca J. (Author), Whittaker, Charles A. (Author), Phyo, Pyae (Author), Shoulders, Matthew D. (Author), Chen, Kenny,Ph. D.Massachusetts Institute of Technology (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences, 2020-05-28T18:49:56Z.
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