Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones
The threat of viral pandemics demands a comprehensive understanding of evolution at the host-pathogen interface. Here, we show that the accessibility of adaptive mutations in influenza nucleoprotein at fever-like temperatures is mediated by host chaperones. Particularly noteworthy, we observe that t...
| Main Authors: | , , , , , , |
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| Other Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS),
2020-05-29T12:42:47Z.
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| Subjects: | |
| Online Access: | Get fulltext |