A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations

A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations

Although the value of proteomics has been demonstrated, cost and scale are typically prohibitive, and gene expression profiling remains dominant for characterizing cellular responses to perturbations. However, high-throughput sentinel assays provide an opportunity for proteomics to contribute at a m...

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Main Authors: Litichevskiy, Lev (Author), Peckner, Ryan (Author), Abelin, Jennifer G. (Author), Asiedu, Jacob K. (Author), Creech, Amanda L. (Author), Davis, John F. (Author), Davison, Desiree (Author), Dunning, Caitlin M. (Author), Egertson, Jarrett D. (Author), Egri, Shawn (Author), Gould, Joshua (Author), Ko, Tak (Author), Johnson, Sarah A. (Author), Lahr, David L. (Author), Lam, Daniel (Author), Liu, Zihan (Author), MacLean, Brendan X. (Author), Lyons, Nicholas J. (Author), Lu, Xiaodong (Author), Mungenast, Alison (Author), Officer, Adam (Author), Natoli, Ted E. (Author), Papanastasiou, Malvina (Author), Patel, Jinal (Author), Sharma, Vagisha (Author), Toder, Courtney (Author), Tubelli, Andrew A. (Author), Young, Jennie Zin-Ney (Author), Carr, Steven A (Author), Golub, Todd (Author), Subramanian, Aravind (Author), MacCoss, Michael J. (Author), Tsai, Li-Huei (Author), Jaffe, Jacob D (Author)
Other Authors: Broad Institute of MIT and Harvard (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2020-06-08T14:09:46Z.
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