A Modified System for the Synthesis of Enantioenriched N -Arylamines through Copper-Catalyzed Hydroamination

Despite significant recent progress in copper-catalyzed enantioselective hydroamination chemistry, the synthesis of chiral N-arylamines, which are frequently found in natural products and pharmaceuticals, has not been realized. Initial experiments with N-arylhydroxylamine ester electrophiles were un...

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Bibliographic Details
Main Authors: Ichikawa, Saki (Author), Zhu, Shaolin (Author), Buchwald, Stephen Leffler (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Wiley, 2020-06-08T20:11:55Z.
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