Binary Targeting of siRNA to Hematologic Cancer Cells In Vivo Using Layer‐by‐Layer Nanoparticles

Binary Targeting of siRNA to Hematologic Cancer Cells In Vivo Using Layer‐by‐Layer Nanoparticles

Using siRNA therapeutics to treat hematologic malignancies has been unsuccessful because blood cancer cells exhibit remarkable resistance to standard transfection methods. Herein, the successful delivery of siRNA therapeutics with a dual-targeted, layer-by-layer nanoparticle (LbL-NP) is reported. Th...

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Bibliographic Details
Main Authors: Choi, Ki Young (Author), Correa Echavarria, Santiago (Author), Min, Jouha (Author), Li, Jiahe (Author), Roy, Sweta (Author), Laccetti, Kristiana H (Author), Dreaden, Erik (Author), Kong, Stephanie (Author), Heo, Roun (Author), Roh, Young Hoon (Author), Lawson, Edward C. (Author), Palmer, Peter A. (Author), Hammond, Paula T (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Wiley, 2020-06-15T18:02:39Z.
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