Programmable CRISPR-responsive smart materials

Programmable CRISPR-responsive smart materials

Stimuli-responsive materials activated by biological signals play an increasingly important role in biotechnology applications. We exploit the programmability of CRISPR-associated nucleases to actuate hydrogels containing DNA as a structural element or as an anchor for pendant groups. After activati...

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Main Authors: English, Max A. (Author), Soenksen Martinez, Luis Ruben (Author), Gayet, Raphael V. (Author), de Puig Guixe, Helena (Author), Angenent-Mari, Nicolaas M. (Author), Mao, Angelo S. (Author), Nguyen, Peter Q. (Author), Collins, James J. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Massachusetts Institute of Technology. Synthetic Biology Center (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2020-06-22T18:59:20Z.
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