Enabling genetic analysis of diverse bacteria with Mobile-CRISPRi

The vast majority of bacteria, including human pathogens and microbiome species, lack genetic tools needed to systematically associate genes with phenotypes. This is the major impediment to understanding the fundamental contributions of genes and gene networks to bacterial physiology and human healt...

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Main Authors: Peters, Jason M. (Author), Koo, Byoung-Mo (Author), Patino, Ramiro (Author), Heussler, Gary E. (Author), Hearne, Cameron C. (Author), Qu, Jiuxin (Author), Inclan, Yuki F. (Author), Hawkins, John S. (Author), Lu, Candy H. S. (Author), Silvis, Melanie R. (Author), Harden, M. Michael (Author), Osadnik, Hendrik (Author), Peters, Joseph E. (Author), Engel, Joanne N. (Author), Dutton, Rachel J. (Author), Grossman, Alan Davis (Author), Gross, Carol A. (Author), Rosenberg, Oren S. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2020-06-30T14:26:02Z.
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