Direct 11CN-labeling of unprotected peptides via palladium-mediated sequential cross-coupling reactions
A practical procedure for [superscript 11]CN-labeling of unprotected peptides has been developed. The method was shown to be highly chemoselective for cysteine over other potentially nucleophilic residues, and the radiolabeled products were synthesized and purified in less than 15 min. Appropriate f...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society (ACS),
2020-06-30T20:55:06Z.
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| Subjects: | |
| Online Access: | Get fulltext |