Mimicking immune signatures of flavivirus infection with targeted adjuvants improves dengue subunit vaccine immunogenicity

Mimicking immune signatures of flavivirus infection with targeted adjuvants improves dengue subunit vaccine immunogenicity

Neutralizing antibodies (nAbs) are a critical component for protection against dengue virus (DENV) infection, but little is known about the immune mechanisms governing their induction and whether such mechanisms can be harnessed for vaccine development. In this study, we profiled the early immune re...

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Bibliographic Details
Main Authors: Bidet, Katell (Author), Ho, Victor (Author), Chu, Collins Wenhan (Author), Naim, Ahmad Nazri Mohamed (Author), Thazin, Khaing (Author), Chan, Kuan Rong (Author), Low, Jenny G. H. (Author), Choy, Milly M. (Author), Wong, Lan Hiong (Author), Florez de Sessions, Paola (Author), Lee, Yie Hou (Author), Hibberd, Martin L. (Author), Ooi, Eng Eong (Author), Fink, Katja (Author), Chen, Jianzhu (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2020-07-07T18:45:10Z.
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