The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn
TorsinA is an ER-resident AAA + ATPase, whose deletion of glutamate E303 results in the genetic neuromuscular disease primary dystonia. TorsinA is an unusual AAA + ATPase that needs an external activator. Also, it likely does not thread a peptide substrate through a narrow central channel, in contra...
| Main Authors: | , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Springer Science and Business Media LLC,
2020-07-07T20:52:53Z.
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| Subjects: | |
| Online Access: | Get fulltext |