CuH-Catalyzed Asymmetric Hydroamidation of Vinylarenes

A CuH-catalyzed enantioselective hydroamidation reaction of vinylarenes has been developed using readily accessible 1,4,2-dioxazol-5-ones as electrophilic amidating reagents. This method provides a straightforward and efficient approach to synthesize chiral amides in good yields with high levels of...

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Bibliographic Details
Main Authors: Zhou, Yujing (Author), Engl, Oliver D. (Author), Bandar, Jeffrey (Author), Chant, Emma D. (Author), Buchwald, Stephen Leffler (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Wiley, 2020-07-08T18:50:03Z.
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