Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion

Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion

The Mad1-Mad2 heterodimer is the catalytic hub of the spindle assembly checkpoint (SAC), which controls M phase progression through a multi-subunit anaphase inhibitor, the mitotic checkpoint complex (MCC) [1, 2]. During interphase, Mad1-Mad2 generates MCC at nuclear pores [3]. After nuclear envelope...

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Main Authors: Rodriguez-Rodriguez (Author), Lewis, Clare (Author), McKinley, Kara Lavidge (Author), Sikirzhytski, Vitali (Author), Corona, Jennifer (Author), Maciejowski, John (Author), Khodjakov, Alexey (Author), Cheeseman, Iain M (Author), Jallepalli, Prasad V. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2020-07-09T14:13:50Z.
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