Replication origin-flanking roadblocks reveal origin-licensing dynamics and altered sequence dependence
In eukaryotes, DNA replication initiates from multiple origins of replication for timely genome duplication. These sites are selected by origin licensing, during which the core enzyme of the eukaryotic DNA replicative helicase, the Mcm2-7 (minichromosome maintenance) complex, is loaded at each origi...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
American Society for Biochemistry & Molecular Biology (ASBMB),
2020-07-15T12:17:28Z.
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| Subjects: | |
| Online Access: | Get fulltext |