Formulations for trans-tympanic antibiotic delivery

Formulations for trans-tympanic antibiotic delivery

We have developed a drug delivery system for prolonged trans-tympanic antibiotic delivery from a single dose administration. Increased permeability to ciprofloxacin of the intact tympanic membrane (TM) was achieved by chemical permeation enhancers (CPEs - bupivacaine, limonene, sodium dodecyl sulfat...

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Bibliographic Details
Main Authors: Khoo, Xiaojuan (Author), Simons, Emmanuel John (Author), Chiang, Homer H. (Author), Hickey, Julia M. (Author), Sabharwal, Vishakha (Author), Pelton, Stephen I. (Author), Rosowski, John J (Author), Langer, Robert (Author), Kohane, Daniel S (Author)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2020-07-15T22:02:12Z.
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