Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers
In vaccine design, antigens are often arrayed in a multivalent nanoparticle form, but in vivo mechanisms underlying the enhanced immunity elicited by such vaccines remain poorly understood. We compared the fates of two different heavily glycosylated HIV antigens, a gp120-derived mini-protein and a l...
Main Authors: | , , , , , , , , , , , , , , , |
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Other Authors: | , , , |
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS),
2020-07-17T20:29:08Z.
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Subjects: | |
Online Access: | Get fulltext |