Limits of Chromosome Compaction by Loop-Extruding Motors

During mitosis, human chromosomes are linearly compacted about 1000-fold by loop-extruding motors. Recent experiments have shown that condensins extrude DNA loops but in a "one-sided" manner. This contrasts with existing models, which predict that symmetric, "two-sided" loop extr...

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Bibliographic Details
Main Authors: Banigan, Edward J (Author), Mirny, Leonid A (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor)
Format: Article
Language:English
Published: American Physical Society (APS), 2020-07-23T16:11:02Z.
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