Limits of Chromosome Compaction by Loop-Extruding Motors
During mitosis, human chromosomes are linearly compacted about 1000-fold by loop-extruding motors. Recent experiments have shown that condensins extrude DNA loops but in a "one-sided" manner. This contrasts with existing models, which predict that symmetric, "two-sided" loop extr...
Main Authors: | , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
American Physical Society (APS),
2020-07-23T16:11:02Z.
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Subjects: | |
Online Access: | Get fulltext |