Limits of Chromosome Compaction by Loop-Extruding Motors
During mitosis, human chromosomes are linearly compacted about 1000-fold by loop-extruding motors. Recent experiments have shown that condensins extrude DNA loops but in a "one-sided" manner. This contrasts with existing models, which predict that symmetric, "two-sided" loop extr...
Main Authors: | Banigan, Edward J (Author), Mirny, Leonid A (Author) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor) |
Format: | Article |
Language: | English |
Published: |
American Physical Society (APS),
2020-07-23T16:11:02Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Limits of Chromosome Compaction by Loop-Extruding Motors
by: Edward J. Banigan, et al.
Published: (2019-07-01) -
Chromosome Compaction by Active Loop Extrusion
by: Marko, John F, et al.
Published: (2017) -
The interplay between asymmetric and symmetric DNA loop extrusion
by: Edward J Banigan, et al.
Published: (2020-12-01) -
The interplay between asymmetric and symmetric DNA loop extrusion
by: Banigan, Edward J, et al.
Published: (2021) -
Chromosome organization by one-sided and two-sided loop extrusion
by: Edward J Banigan, et al.
Published: (2020-04-01)