Class I Histone Deacetylase Inhibition by Tianeptinaline Modulates Neuroplasticity and Enhances Memory

Through epigenetic and other regulatory functions, the histone deacetylase (HDAC) family of enzymes has emerged as a promising therapeutic target for central nervous system and other disorders. Here we report on the synthesis and functional characterization of new HDAC inhibitors based structurally...

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Bibliographic Details
Main Authors: Zhao, Wen-Ning (Author), Ghosh, Balaram (Author), Tyler, Marshall (Author), Lalonde, Jasmin (Author), Joseph, Nadine F. (Author), Kosaric, Nina (Author), Fass, Daniel M. (Author), Tsai, Li-Huei (Author), Mazitschek, Ralph (Author), Haggarty, Stephen J. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2020-07-24T17:30:05Z.
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