Crystal structure and catalytic mechanism of the essential m¹ G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa

© 2019 Cold Spring Harbor Laboratory Press. All rights reserved. The tRNA (m1G37) methyltransferase TrmD catalyzes m1G formation at position 37 in many tRNA isoacceptors and is essential in most bacteria, which positions it as a target for antibiotic development. In spite of its crucial role, little...

Full description

Bibliographic Details
Main Authors: Prestwich, Erin (Author), DeMott, Michael S. (Author), Dedon, Peter C (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory, 2020-07-30T19:51:24Z.
Subjects:
Online Access:Get fulltext