Longitudinal immunosequencing in healthy people reveals persistent T cell receptors rich in highly public receptors

Longitudinal immunosequencing in healthy people reveals persistent T cell receptors rich in highly public receptors

Background: The adaptive immune system maintains a diversity of T cells capable of recognizing a broad array of antigens. Each T cell's specificity for antigens is determined by its T cell receptors (TCRs), which together across all T cells form a repertoire of millions of unique receptors in e...

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Bibliographic Details
Main Authors: Chu, Nathaniel David (Author), Birnbaum, Michael E (Author), Alm, Eric J (Author), Bi, Haixin S (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Microbiology Graduate Program (Contributor), Massachusetts Institute of Technology. Center for Microbiome Informatics and Therapeutics (Contributor), Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Civil and Environmental Engineering (Contributor)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2020-07-31T11:44:53Z.
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