Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons

Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons

Understanding neurological diseases requires tractable genetic systems, and engineered three-dimensional (3D) neural tissues are an attractive choice. Yet how the cellular transcriptomic profiles in these tissues are affected by the encapsulating materials and are related to the human brain transcri...

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Main Authors: Tekin, Halil (Author), Simmons, Sean (Author), Cummings, Beryl (Author), Gao, Linyi (Author), Adiconis, Xian (Author), Hession, Cynthia C. (Author), Ghoshal, Ayan (Author), Dionne, Danielle (Author), Choudhury, Sourav (Author), Yesilyurt, Volkan (Author), Sanjana, Neville E (Author), Shi, Xi (Author), Lu, Congyi (Author), Heidenreich, Matthias (Author), Pan, Jen Q. (Author), Levin, Joshua Z. (Author), Zhang, Feng (Author)
Other Authors: McGovern Institute for Brain Research at MIT (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2020-08-05T18:19:23Z.
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