Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA

Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA

Allele-specific protein-RNA binding is an essential aspect that may reveal functional genetic variants (GVs) mediating post-transcriptional regulation. Recently, genome-wide detection of in vivo binding of RNA-binding proteins is greatly facilitated by the enhanced crosslinking and immunoprecipitati...

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Main Authors: Yang, Ei-Wen (Author), Bahn, Jae Hoon (Author), Yun-Hua Hsiao, Esther (Author), Tan, Boon Xin (Author), Sun, Yiwei (Author), Fu, Ting (Author), Zhou, Bo (Author), Van Nostrand, Eric L. (Author), Pratt, Gabriel A. (Author), Freese, Peter Dale (Author), Wei, Xintao (Author), Quinones-Valdez, Giovanni (Author), Urban, Alexander E. (Author), Graveley, Brenton R. (Author), Burge, Christopher B (Author), Yeo, Gene W. (Author), Xiao, Xinshu (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Springer Nature, 2020-08-07T18:20:38Z.
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