Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep (MINDDS): Protocol for a randomised, double-blind, parallel-arm, placebo-controlled trial

Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep (MINDDS): Protocol for a randomised, double-blind, parallel-arm, placebo-controlled trial

Introduction Delirium, which is prevalent in postcardiac surgical patients, is an acute brain dysfunction characterised by disturbances in attention, awareness and cognition not explained by a pre-existing neurocognitive disorder. The pathophysiology of delirium remains poorly understood. However, b...

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Main Authors: Shelton, Kenneth T (Author), Qu, Jason (Author), Bilotta, Federico (Author), Brown, Emery Neal (Author), Cudemus, Gaston (Author), D'Alessandro, David A (Author), Deng, Hao (Author), DiBiasio, Alan (Author), Gitlin, Jacob A (Author), Hahm, Eunice Y (Author), Hobbs, Lauren E (Author), Houle, Timothy T (Author), Ibala, Reine (Author), Loggia, Marco (Author), Pavone, Kara J (Author), Shaefi, Shahzad (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor)
Format: Article
Language:English
Published: BMJ Publishing Group, 2020-08-14T22:58:30Z.
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