A data-driven method for quantifying the impact of a genetic circuit on its host

A data-driven method for quantifying the impact of a genetic circuit on its host

Genetic circuits aredesigned to implement certain logic in living cells, keeping burden on the host cell minimal. However, manipulating the genome often will have a significant impact for various reasons (usage of the cell machinery to express new genes, toxicity of genes, interactions with native g...

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Bibliographic Details
Main Authors: Dorfan, Yuval (Author), Espah Borujeni, Amin (Author), Park, YongJin (Author), Saxena, Uma (Author), Gondon, Ben (Author), Voigt, Christopher A. (Author), Yeung, Enoch (Author)
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: IEEE, 2020-09-08T17:14:07Z.
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