DNA Phosphorothioate Modifications Are Widely Distributed in the Human Microbiome

The DNA phosphorothioate (PT) modification existing in many prokaryotes, including bacterial pathogens and commensals, confers multiple characteristics, including restricting gene transfer, influencing the global transcriptional response, and reducing fitness during exposure to chemical mediators of...

Full description

Bibliographic Details
Main Authors: Sun, Yihua (Author), Kong, Lingxin (Author), Wu, Guojun (Author), Cao, Bo (Author), Pang, Xiaoyan (Author), Deng, Zixin (Author), Dedon, Peter C (Author), Zhang, Chenhong (Author), You, Delin (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor)
Format: Article
Language:English
Published: Multidisciplinary Digital Publishing Institute, 2020-09-24T14:07:18Z.
Subjects:
Online Access:Get fulltext