Calprotectin influences the aggregation of metal-free and metal-bound amyloid-β by direct interaction

Calprotectin influences the aggregation of metal-free and metal-bound amyloid-β by direct interaction

Proteins from the S100 family perform numerous functions and may contribute to Alzheimer's disease (AD). Herein, we report the effects of S100A8/S100A9 heterooligomer calprotectin (CP) and the S100B homodimer on metal-free and metal-bound amyloid-β (Aβ; Aβ 40 and Aβ 42 ) aggregation in vitro. S...

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Main Authors: Lee, Hyuck Jin (Author), Savelieff, Masha G. (Author), Kang, Juhye (Author), Brophy, Megan Brunjes (Author), Nakashige, Toshiki George (Author), Lee, Shin Jung C. (Author), Nolan, Elizabeth Marie (Author), Lim, Mi Hee (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry (RSC), 2020-10-16T14:57:16Z.
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