Prevention of tuberculosis in macaques after intravenous BCG immunization

Prevention of tuberculosis in macaques after intravenous BCG immunization

Mycobacterium tuberculosis (Mtb) is the leading cause of death from infection worldwide1. The only available vaccine, BCG (Bacillus Calmette-Guérin), is given intradermally and has variable efficacy against pulmonary tuberculosis, the major cause of mortality and disease transmission1,2. Here we sh...

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Main Authors: Darrah, Patricia A. (Author), Zeppa, Joseph J. (Author), Maiello, Pauline (Author), Hackney, Joshua A. (Author), Wadsworth, Marc Havens (Author), Hughes, Travis K. (Author), Pokkali, Supriya (Author), Swanson II, Phillip A. (Author), Grant, Nicole L. (Author), Rodgers, Mark A. (Author), Kamath, Megha (Author), Causgrove, Chelsea M. (Author), Laddy, Dominick J. (Author), Bonavia, Aurelio (Author), Casimiro, Danilo (Author), Lin, Philana Ling (Author), Klein, Edwin (Author), White, Alexander G. (Author), Scanga, Charles A. (Author), Shalek, Alexander K (Author), Roederer, Mario (Author), Flynn, JoAnne L. (Author), Seder, Robert A. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor), Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2020-10-27T19:46:57Z.
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