Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma

Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma

The relationship between promoter proximal transcription factor-associated gene expression and super-enhancer-driven transcriptional programs are not well defined. However, their distinct genomic occupancy suggests a mechanism for specific and separable gene control. We explored the transcriptional...

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Main Authors: Fulciniti, Mariateresa (Author), Lin, Charles Y. (Author), Samur, Mehmet K. (Author), Lopez, Michael A. (Author), Singh, Irtisha (Author), Lawlor, Matthew A. (Author), Szalat, Raphael E. (Author), Ott, Christopher J. (Author), Avet-Loiseau, Herve' (Author), Anderson, Kenneth C. (Author), Young, Richard A. (Author), Bradner, James E. (Author), Munshi, Nikhil C. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2020-11-02T23:31:10Z.
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