Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

Large-scale deep-coverage whole-genome sequencing (WGS) is now feasible and offers potential advantages for locus discovery. We perform WGS in 16,324 participants from four ancestries at mean depth >29X and analyze genotypes with four quantitative traits-plasma total cholesterol, low-density lipo...

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Main Authors: Natarajan, Pradeep (Author), Peloso, Gina M. (Author), Zekavat, Seyedeh Maryam (Author), Montasser, May (Author), Ganna, Andrea (Author), Chaffin, Mark (Author), Khera, Amit V. (Author), Zhou, Wei (Author), Bloom, Jonathan M. (Author), Engreitz, Jesse M. (Author), Ernst, Jason (Author), O'Connell, Jeffrey R. (Author), Ruotsalainen, Sanni E. (Author), Alver, Maris (Author), Manichaikul, Ani (Author), Johnson, W. Craig (Author), Perry, James A. (Author), Poterba, Timothy (Author), Seed, Cotton (Author), Surakka, Ida L. (Author), Esko, Tonu (Author), Ripatti, Samuli (Author), Salomaa, Veikko (Author), Correa, Adolfo (Author), Vasan, Ramachandran S. (Author), Kellis, Manolis (Author), Neale, Benjamin M. (Author), Lander, Eric S. (Author), Abecasis, Goncalo (Author), Mitchell, Braxton (Author), Rich, Stephen S. (Author), Wilson, James G. (Author), Cupples, L. Adrienne (Author), Rotter, Jerome I. (Author), Willer, Cristen J. (Author), Kathiresan, Sekar (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2020-11-16T16:24:17Z.
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