Npas4 Is a Critical Regulator of Learning-Induced Plasticity at Mossy Fiber-CA3 Synapses during Contextual Memory Formation

Npas4 Is a Critical Regulator of Learning-Induced Plasticity at Mossy Fiber-CA3 Synapses during Contextual Memory Formation

Synaptic connections between hippocampal mossy fibers (MFs) and CA3 pyramidal neurons are essential for contextual memory encoding, but the molecular mechanisms regulating MF-CA3 synapses during memory formation and the exact nature of this regulation are poorly understood. Here we report that the a...

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Main Authors: Weng, Feng-Ju (Author), Garcia, Rodrigo (Author), Lutzu, Stefano (Author), Alviña, Karina (Author), Zhang, Yuxiang (Author), Dushko, Margaret (Author), Ku, Taeyun (Author), Zemoura, Khaled (Author), Rich, David (Author), Garcia-Dominguez, Dario (Author), Hung, Matthew (Author), Yelhekar, Tushar D (Author), Sørensen, Andreas Toft (Author), Xu, Weifeng (Author), Chung, Kwanghun (Author), Castillo, Pablo E. (Author), Lin, Yingxi (Author)
Other Authors: McGovern Institute for Brain Research at MIT (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor), Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Harvard University- (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2020-12-15T22:43:11Z.
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