Synthesis of Pyrroles through the CuH-Catalyzed Coupling of Enynes and Nitriles
Herein, we describe an efficient method to prepare polysubstituted pyrroles via a copper hydride (CuH)-catalyzed enyne-nitrile coupling reaction. This protocol accommodates both aromatic and aliphatic substituents and a broad range of functional groups, providing a variety of N-H pyrroles in good yi...
Main Authors: | Zhou, Yujing (Author), Zhou, Lin (Author), Jesikiewicz, Luke T (Author), Liu, Peng (Author), Buchwald, Stephen Leffler (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry (Contributor) |
Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS),
2021-01-14T20:04:54Z.
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Subjects: | |
Online Access: | Get fulltext |
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