Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Long non-coding RNAs (lncRNAs) are a growing focus of cancer genomics studies, creating the need for a resource of lncRNAs with validated cancer roles. Furthermore, it remains debated whether mutated lncRNAs can drive tumorigenesis, and whether such functions could be conserved during evolution. Her...

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Main Authors: Carlevaro-Fita, Joana (Author), Lanzós, Andrés (Author), Feuerbach, Lars (Author), Hong, Chen (Author), Mas-Ponte, David (Author), Pedersen, Jakob Skou (Author), Johnson, Rory (Author), Kellis, Manolis (Author), PCAWG Drivers and Functional Interpretation Group (Author)
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2021-01-19T20:25:17Z.
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