De Novo Discovery of High-Affinity Peptide Binders for the SARS-CoV-2 Spike Protein

De Novo Discovery of High-Affinity Peptide Binders for the SARS-CoV-2 Spike Protein

The β-coronavirus SARS-CoV-2 has caused a global pandemic. Affinity reagents targeting the SARS-CoV-2 spike protein are of interest for the development of therapeutics and diagnostics. We used affinity selection-mass spectrometry for the rapid discovery of synthetic high-affinity peptide binders for...

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Bibliographic Details
Main Authors: Pomplun, Sebastian Johannes (Author), Jbara, Muhammad (Author), Quartararo, Anthony James (Author), Zhang, Genwei (Author), Brown, Joseph S. (Author), Lee, Yen-Chun (Author), Ye, Xiyun (Author), Hanna, Stephanie (Author), Pentelute, Bradley L. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2021-02-04T17:49:27Z.
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