Bayesian Adaptive Clinical Trials for Anti-Infective Therapeutics During Epidemic Outbreaks
In the midst of epidemics such as COVID-19, therapeutic candidates are unlikely to be able to complete the usual multiyear clinical trial and regulatory approval process within the course of an outbreak. We apply a Bayesian adaptive patient-centered model-which minimizes the expected harm of false p...
| Main Authors: | , , , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
MIT Press,
2021-02-17T22:28:00Z.
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| Subjects: | |
| Online Access: | Get fulltext |