Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme

Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme

Abstract: Glycyl radical enzymes (GREs) utilize a glycyl radical cofactor to carry out a diverse array of chemically challenging enzymatic reactions in anaerobic bacteria. Although the glycyl radical is a powerful catalyst, it is also oxygen sensitive such that oxygen exposure causes cleavage of the...

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Bibliographic Details
Main Authors: Bowman, Sarah E. J. (Author), Backman, Lindsey R. (Author), Bjork, Rebekah E. (Author), Andorfer, Mary (Author), Yori, Santiago (Author), Caruso, Alessio (Author), Stultz, Collin M (Author), Drennan, Catherine L (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2021-02-23T23:00:04Z.
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