Enhancing phage therapy through synthetic biology and genome engineering

Enhancing phage therapy through synthetic biology and genome engineering

The antimicrobial and therapeutic efficacy of bacteriophages is currently limited, mostly due to rapid emergence of phage-resistance and the inability of most phage isolates to bind and infect a broad range of clinical strains. Here, we discuss how phage therapy can be improved through recent advanc...

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Bibliographic Details
Main Authors: Lenneman, Bryan R (Author), Fernbach, Jonas (Author), Loessner, Martin J (Author), Lu, Timothy K (Author), Kilcher, Samuel (Author)
Other Authors: Massachusetts Institute of Technology. Research Laboratory of Electronics (Contributor), Massachusetts Institute of Technology. Synthetic Biology Center (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2021-04-01T17:38:41Z.
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