Widespread Accumulation of Ribosome-Associated Isolated 3' UTRs in Neuronal Cell Populations of the Aging Brain

Widespread Accumulation of Ribosome-Associated Isolated 3' UTRs in Neuronal Cell Populations of the Aging Brain

Particular brain regions and cell populations exhibit increased susceptibility to aging-related stresses. Here, we describe the age-specific and brain-region-specific accumulation of ribosome-associated 3' UTR RNAs that lack the 5' UTR and open reading frame. Our study reveals that this ph...

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Bibliographic Details
Main Authors: Sudmant, Peter (Author), Lee, Hyeseung (Author), Dominguez, Daniel (Author), Heiman, Myriam (Author), Burge, Christopher B. (Author)
Other Authors: Picower Institute for Learning and Memory (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2021-04-28T14:37:51Z.
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