Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

SARS-CoV-2 infection can cause severe respiratory COVID-19. However, many individuals present with isolated upper respiratory symptoms, suggesting potential to constrain viral pathology to the nasopharynx. Which cells SARS-CoV-2 primarily targets and how infection influences the respiratory epitheli...

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Main Authors: Ziegler, Carly (Author), Miao, Vincent N. (Author), Owings, Anna H. (Author), Navia, Andrew W. (Author), Tang, Ying (Author), Bromley, Joshua D. (Author), Lotfy, Peter (Author), Sloan, Meredith (Author), Laird, Hannah (Author), Williams, Haley B. (Author), George, Micayla (Author), Drake, Riley S. (Author), Christian, Taylor (Author), Parker, Adam (Author), Sindel, Campbell B. (Author), Burger, Molly W. (Author), Pride, Yilianys (Author), Hasan, Mohammad (Author), Abraham, George E. (Author), Senitko, Michal (Author), Robinson, Tanya O. (Author), Shalek, Alexander K (Author), Glover, Sarah C. (Author), Horwitz, Bruce H. (Author), Ordovas-Montanes, Jose (Author)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Massachusetts Institute of Technology. Microbiology Graduate Program (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2021-08-25T16:25:18Z.
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