Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization

Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization

Rationally designed protein subunit vaccines are being developed for a variety of viruses including influenza, RSV, SARS-CoV-2, and HIV. These vaccines are based on stabilized versions of the primary targets of neutralizing antibodies on the viral surface, namely, viral fusion glycoproteins. While t...

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Bibliographic Details
Main Authors: Turner, Hannah L. (Author), Andrabi, Raiees (Author), Cottrell, Christopher A. (Author), Richey, Sara T. (Author), Song, Ge (Author), Callaghan, Sean (Author), Anzanello, Fabio (Author), Moyer, Tyson J. (Author), Abraham, Wuhbet (Author), Melo, Mariane Bandeira (Author), Silva, Murillo (Author), Scaringi, Nicole (Author), Rakasz, Eva G. (Author), Sattentau, Quentin J. (Author), Irvine, Darrell J (Author), Burton, Dennis R. (Author), Ward, Andrew B. (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2021-08-31T17:06:16Z.
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