Multi-Omics Characterization of Inflammatory Bowel Disease-Induced Hyperplasia/Dysplasia in the Rag2−/−/Il10−/− Mouse Model

Epigenetic dysregulation is hypothesized to play a role in the observed association between inflammatory bowel disease (IBD) and colon tumor development. In the present work, DNA methylome, hydroxymethylome, and transcriptome analyses were conducted in proximal colon tissues harvested from the <i...

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Main Authors: Han, Qiyuan (Author), Kono, Thomas J. Y. (Author), Knutson, Charles G. (Author), Parry, Nicola M. (Author), Seiler, Christopher L. (Author), Fox, James G. (Author), Tannenbaum, Steven R. (Author), Tretyakova, Natalia Y. (Author)
Format: Article
Language:English
Published: MDPI AG, 2022-03-14T18:01:22Z.
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