Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro
Bacterial sepsis and severe COVID-19 share similar clinical manifestations and are both associated with dysregulation of the myeloid cell compartment. We previously reported an expanded CD14⁺ monocyte state, MS1, in patients with bacterial sepsis and validated expansion of this cell subpopulation in...
Main Authors: | Reyes, Miguel (Author), Filbin, Michael R. (Author), Bhattacharyya, Roby P. (Author), Sonny, Abraham (Author), Mehta, Arnav (Author), Billman, Kianna (Author), Kays, Kyle R. (Author), Pinilla-Vera, Mayra (Author), Benson, Maura E. (Author), Cosimi, Lisa A. (Author), Hung, Deborah T. (Author), Levy, Bruce D. (Author), Villani, Alexandra-Chloe (Author), Sade-Feldman, Moshe (Author), Baron, Rebecca M. (Author), Goldberg, Marcia B. (Author), Blainey, Paul C (Author), Hacohen, Nir (Author) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor) |
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS),
2021-09-24T18:11:41Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
An immune-cell signature of bacterial sepsis
by: Reyes, Miguel, et al.
Published: (2020) -
Targeting individual cells by barcode in pooled sequence libraries
by: Villani, Alexandra-Chloé, et al.
Published: (2019) -
Multiplexed enrichment and genomic profiling of peripheral blood cells reveal subset-specific immune signatures
by: Vickers, Dwayne, et al.
Published: (2019) -
MicroRNA-132 is a Physiological Regulator of Hematopoietic Stem Cell Function and B-cell Development
by: Mehta, Arnav
Published: (2015) -
Exponentially faster implementations of Select(H) for fermionic Hamiltonians
by: Kianna Wan
Published: (2021-01-01)