Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding

Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding

Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works Mechanisms of resistance to cancer immunotherapy remain poorly understood. Lymphocyte activation gene-3 (LAG3) signaling is regulated...

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Main Authors: Andrews, Lawrence P (Author), Somasundaram, Ashwin (Author), Moskovitz, Jessica M (Author), Szymczak-Workman, Andrea L (Author), Liu, Chang (Author), Cillo, Anthony R (Author), Lin, Huang (Author), Normolle, Daniel P (Author), Moynihan, Kelly Dare (Author), Taniuchi, Ichiro (Author), Irvine, Darrell J (Author), Kirkwood, John M (Author), Lipson, Evan J (Author), Ferris, Robert L (Author), Bruno, Tullia C (Author), Workman, Creg J (Author), Vignali, Dario AA (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2021-10-18T14:57:59Z.
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